In a study published inthe journalMedical Care, a team from Houston Methodist Hospital used the Sepsis Early Recognition and Response Initiative (SERRI) to uncover important insights about the development, progression, and outcomes of sepsis in the hospital setting.
Septicemia is the most expensive condition treated in United States hospitals, and is the cause of approximately 5 percent of the total cost of all hospitalizations in the United States.
The study examined hospital utilization patterns for the timing of diagnosis, severity of sepsis, and multiple hospital stay rates, as well as the differences between hospital types that treated these patients.
Researchers aimed “to establish a baseline for the incidence of sepsis by severity and presence on admission in acute care hospital settings before implementation of a broad sepsis screening and response initiative.”
The authors conducted a retrospective cohort study with the data from five community hospitals and one academic medical center in Texas. They examined the hospital discharge data from 5,672 patients who were 18 years or older between February 2012 to January 2013.
Data was collected using SERRI, a program that is funded by the Centers for Medicare and Medicaid Innovation (CMMI). SERRI uses big data analytics to generate useful insights about how to detect sepsis, which is overwhelmingly misdiagnosed. Hospitals submit deidentified discharge information to SERRI, which then provides analysis and data validation.
The resulting data can be integrated into a screening tool in the electronic health record (EHR), used for educating nurses and staff about early recognition of sepsis, and standardizing a procedure for rapid response.
During the study, the team found that 85 percent of sepsis patients had the condition on admission and the rest acquired it at the hospital. The inpatient death rate was 17.2 percent overall, and was highest for hospital-acquired sepsis. The mortality rate was 38.6 percent for sepsis acquired in the medical setting and 29.2 percent when the condition was related to surgery.;